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Place the following events involved in drug addiction in the correct sequence. I-The synapse becomes less sensitive,and normal function can only continue in the presence of the drug. II-CNS responds to increased firing by decreasing the number of drug receptors on the cell membrane. III-Drug molecule prevents receptor endocytosis and causes overstimulation of the postsynaptic cell.


A) I,II,III
B) III,II,I
C) II,III,I
D) III,I,II

E) None of the above
F) A) and D)

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K+ channels in the heart do not have binding sites for ACh,yet parasympathetic release of ACh causes outward flux of K+ from heart cells.How does this occur?


A) ACh triggers release of epinephrine from the adrenal glands,which in turn causes K+ flux out of heart cells.
B) ACh binds to a G-protein coupled receptor on heart cells,and the G protein alpha subunit binds to a separate K+ channel and causes it to open.
C) Parasympathetic neurons activate sympathetic neurons,which directly cause K+ flux from heart cells.
D) ACh binds and activates a K+ pump on heart cells.

E) All of the above
F) None of the above

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Which of the following are examples of biogenic amines?


A) epinephrine and endorphins
B) GABA and serotonin
C) epinephrine,dopamine,and GABA
D) epinephrine,dopamine,and serotonin
E) epinephrine,norepinephrine,dopamine,and serotonin

F) A) and D)
G) B) and C)

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When a neuron is not firing,the sodium-potassium pump is inactive.

A) True
B) False

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The doctor informs you that your grandmother's stroke has caused damage to Wernicke's area.Which activity is likely to become more difficult for her?


A) walking
B) doing laundry
C) having a conversation
D) sleeping
E) mathematical calculations

F) A) and B)
G) A) and E)

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Nerve impulses are electrical signals measured across which structure?


A) lipid sheath of Schwann cell
B) plasma membrane of neuron
C) synapse
D) neuromuscular junction

E) B) and C)
F) A) and D)

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Which ion channel is primarily responsible for the action potential?


A) the voltage-gated sodium channel
B) the voltage-gated potassium channel
C) the ligand-gated sodium channel
D) the ligand-gated potassium channel
E) the nongated sodium channel

F) A) and E)
G) None of the above

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Which animal phylum lacks a network of nerve cells for gathering information from the environment?


A) Porifera - sponges
B) Cnidaria - jellyfish,sea anemones
C) Platyhelminthes -- flatworms
D) Nematoda - roundworms
E) Mollusca - octopus,squid,clams,snails,and other mollusks

F) A) and B)
G) A) and C)

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The spinal cord is enclosed by the vertebral column and layers of protective membranes.What are these membranes called?


A) neural net
B) white matter
C) dorsal root
D) meninges
E) viscera

F) A) and B)
G) A) and C)

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Which area of the cerebral cortex is important for the formulation of thoughts into speech?


A) Broca's area
B) the pons
C) the medulla oblongata
D) Wernicke's area
E) the cerebellum

F) A) and E)
G) C) and D)

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A region of the brain receives both sensory information from ascending nerve tracts and motor commands from the cortex and cerebellum.This region plays an important role in motor control.Which region is it?


A) basal ganglia
B) pituitary gland
C) parietal lobe
D) thalamus
E) medulla oblongata

F) C) and D)
G) B) and D)

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In vertebrates,the ________ nervous system is composed of the brain and the spinal cord.


A) peripheral
B) central
C) somatic
D) autonomic
E) sympathetic

F) A) and B)
G) A) and C)

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What is the primary function of the hindbrain in vertebrates?


A) temperature control
B) integration of sensory data
C) memory storage
D) control of the heartbeat
E) coordination of motor reflexes

F) All of the above
G) A) and B)

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Which of the following is not part of the peripheral nervous system?


A) sympathetic division of the autonomic nervous system
B) spinal cord
C) parasympathetic division of the autonomic nervous system
D) somatic nervous system
E) sensory pathways

F) All of the above
G) B) and C)

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What is the name for the gap into which neurotransmitters are released?


A) gap junction
B) synaptic cleft
C) postsynaptic membrane
D) presynaptic membrane
E) impulse channel

F) C) and E)
G) A) and B)

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Sodium ions are single atoms.Why can't they simply diffuse through the cell membrane's lipid bilayer?


A) Since they are charged,ions can't cross the hydrophobic center of the membrane without a channel or pump.
B) Sodium ions are covalently attached in groups of three,which are too large to diffuse easily.
C) Ions do traverse the membrane easily,but the sodium-potassium pump moves them back across.
D) Chelator proteins capture any ions that start to cross the bilayer.

E) None of the above
F) B) and D)

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How do temporal and spatial summation improve the processing power of the brain?


A) Temporal summation allows circadian rhythms to regulate neuronal activity.Spatial summation allows latitude to regulate neuronal activity.
B) Temporal summation allows a neuron to fire prolonged action potentials,and spatial summation allows a neuron to synapse onto new targets.
C) Temporal and spatial summation both make the neuron more likely to fire action potentials.
D) Temporal summation allows a neuron to recognize a persistent signal from a single presynaptic cell,and spatial summation allows a neuron to recognize a broad signal from multiple presynaptic cells.

E) A) and B)
F) C) and D)

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At myelinated areas of the axon (i.e.between nodes of Ranvier) ,which of the following statements is true?


A) There is an increased number of voltage-gated sodium channels.
B) There is increased resistance across the membrane.
C) There is increased capacitance across the membrane.
D) There is increased transport of potassium across the membrane.

E) None of the above
F) A) and C)

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Why are mammalian reflexes so fast? (Check all that apply.)


A) They use neurons with extra-wide axons.
B) They complete the sensory input-to-motor output circuit in only 2-3 neurons.
C) They do not send signals to the brain and back.
D) They activate a large number of sensory neurons,which speeds things up after the motor neuron performs spatial summation.
E) There was a selective advantage to evolve rapid responses to certain types of stimuli.

F) B) and D)
G) C) and E)

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A neuron that engages in spatial summation acquires a mutation that causes dendrite overgrowth and promiscuous synapsing.What is the likely outcome?


A) abnormally low frequency of action potentials
B) summation will not occur
C) abnormally high frequency of action potentials
D) action potentials with stronger depolarization

E) None of the above
F) A) and D)

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