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In humans,if nondisjunction led to an individual with a genotype of XO,that person would


A) be female because each cell lacks a Y chromosome.
B) be male because each cell has only one X chromosome.
C) display both male and female characteristics.
D) not survive.

E) B) and C)
F) A) and B)

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Sickle cell anemia is caused by a defect in the


A) oxygen-carrying pigment hemoglobin.
B) ability of the blood to clot.
C) ability of red blood cells to fight infection.
D) chloride ion transport protein.

E) A) and B)
F) C) and D)

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At an autosomal gene locus in humans,the allele for brown eyes is dominant over the allele for blue eyes.At another gene locus,located on the X chromosome,a recessive allele produces colorblindness while the dominant allele produces normal color vision.A heterozygous brown-eyed woman who is a carrier of colorblindness has a child with a blue-eyed man who is not colorblind.An ultrasound test shows that the child is a girl.What is the probability that she will be colorblind? (Enter the probability as a percent.Enter the number only without the percent sign.For example,enter 100% as 100 and enter 12.5% as 12.5)

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Why can't you use mitochondrial DNA to distinguish between these two suspects?


A) The sequence of mitochondrial DNA has not yet been determined.
B) The brothers share the same mitochondrial DNA.
C) There are no molecular techniques available that allow one to analyze mitochondrial DNA.
D) Because mitochondrial DNA is inherited in a paternal pattern.

E) A) and B)
F) A) and C)

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B

Morgan's student Sturtevant demonstrated that the recombination frequencies between a series of linked genes is additive.Examine the following recombination data from Sturtevant,and determine the proper order of the genes on the Drosophila X chromosome.Assume y is in the 0.0 position. Morgan's student Sturtevant demonstrated that the recombination frequencies between a series of linked genes is additive.Examine the following recombination data from Sturtevant,and determine the proper order of the genes on the Drosophila X chromosome.Assume y is in the 0.0 position.    A) y m v w B) y w v m C) y m w v D) y w m v


A) y m v w
B) y w v m
C) y m w v
D) y w m v

E) A) and B)
F) None of the above

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A test cross can be used to do all of the following except


A) determine whether an individual that displays a dominant phenotype is homozygous for the trait.
B) determine whether an individual that displays a dominant phenotype is heterozygous for the trait.
C) gather genotype information from phenotype information.
D) identify the chromosome on which a gene is located.

E) A) and D)
F) B) and C)

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Genetic exchange between 2 homologous chromosomes is called


A) synapsis.
B) pleiotropy.
C) crossing over.
D) allelic exchange.
E) independent assortment.

F) A) and B)
G) None of the above

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In humans,the male has an X and a Y sex chromosome.The human female has two X chromosomes.In birds,the female has a Z and a W sex chromosome while the male has two Z chromosomes.Which of the following statements is accurate about which parent determines the gender of the offspring based on inheritance of the necessary sex chromosome?


A) In humans and birds,the male determines the gender of all the offspring.
B) In humans and birds,the female determines the gender of all the offspring.
C) In humans,the male determines the gender of the offspring,and in birds the female determines the gender.
D) In humans,the female determines the gender of the offspring,and in birds the male determines the gender.
E) Determination of the gender of any human or bird offspring is related to the environmental conditions at the time of conception.

F) B) and D)
G) A) and D)

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The number of allele pairs that assort independently in an organism is generally much higher than the number of chromosome pairs.This phenomenon is due to


A) independent assortment.
B) segregation.
C) crossing over.
D) sex-linkage.
E) chromosome inactivation.

F) A) and D)
G) C) and E)

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Which statement about calico cats is false?


A) Calico cats can be male or female.
B) The different colored fur is due to the inactivation of one X chromosome.
C) The variation in coat color is an example of an epistatic interaction.
D) Calico cats are genetic mosaics.

E) All of the above
F) A) and B)

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If an XY human had a genetic disorder that causes insensitivity to androgens,that person's genotype and phenotype would be


A) XX,female.
B) XX,male.
C) XY,female.
D) XY,male.

E) C) and D)
F) All of the above

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In Morgan's experiments,the white eye allele in Drosophila was shown to be


A) located on the X chromosome.
B) located on the Y chromosome.
C) dominant.
D) located on an autosome.
E) codominant.

F) D) and E)
G) B) and E)

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Occasionally,chromosomes fail to separate during meiosis,leading to daughter cells that have an abnormal number of chromosomes.This phenomenon is called


A) epistasis.
B) nondisjunction.
C) crossing over.
D) pleiotropy.
E) chromosome inactivation.

F) B) and E)
G) C) and D)

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A genetic ________ indicates the distances between gene loci measured in terms of the frequency of recombination.


A) map
B) profile
C) pedigree
D) clone
E) karyotype

F) All of the above
G) A) and B)

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A

In Drosophila,the allele red eyes (bw+) is dominant to the allele for brown eyes (bw) .At another gene locus on the same chromosome,the allele for thin wing veins (hv+) is dominant to the allele for heavy wing veins (hv) .Flies homozygous for bw and hv+ are crossed to flies homozygous for bw+ and hv to obtain doubly heterozygous F1 progeny. -What is the relationship between recombination frequency and the actual physical distance on a chromosome?


A) As physical distance increases,the recombination frequency increases in a linear fashion.
B) As physical distance increases,the recombination frequency decreases in a linear fashion.
C) As physical distance increases,the recombination frequency first increases in a linear fashion,but gradually levels off to a frequency of 0.5.
D) As physical distance increases,the recombination frequency first increases,but then decreases.

E) All of the above
F) C) and D)

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The theory of chromosomal inheritance was first proposed by


A) Mendel.
B) Morgan.
C) Knight.
D) Sutton.
E) Stern.

F) A) and B)
G) A) and C)

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In humans,hemophilia is caused by a recessive allele on the X chromosome.Suppose a man with hemophilia has children with a healthy woman whose mother had hemophilia.If an ultrasound test shows that their first child is a girl,what is the probability that she has hemophilia? (Enter the probability as a percent.Enter the number only without the percent sign.For example,enter 100% as 100 and enter 12.5% as 12.5)

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In Drosophila,the sex of an individual is determined by


A) 1 pair of alleles.
B) the number of X chromosomes.
C) the number of Y chromosomes.
D) 1 pair of autosomes.
E) 2 pairs of alleles.

F) All of the above
G) A) and E)

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A 39-year-old woman and 42-year-old man are expecting a child; the woman is 6 weeks pregnant.The pregnancy is categorized as high risk due to the age of the parents,and the couple would like to have prenatal testing done to see if any genetic disorders are present in the fetus.Their doctor should suggest


A) amniocentesis.
B) genetic counseling.
C) chorionic villi sampling.
D) a pedigree analysis.

E) B) and C)
F) A) and D)

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In a two-point cross to map genes A and B,you obtained 98 recombinant types and 902 parental types among the offspring.How far apart are these genes?


A) 9.8 cM
B) 0) 98 cM
C) 90.2 cM
D) 9.02 cM
E) .098 cM

F) A) and E)
G) B) and E)

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A

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