Question 1

Which of the following is NOT an antigen presenting cell?

Accepted Answer

A)  Cytotoxic T lymphocyte
B)  Macrophage
C)  Dendritic cell
D)  B lymphocyte
E)  All of the above are antigen presenting cells.F) D) and E)
G) A) and E) A

Question 2

Antigen presenting cells,like dendritic cells,interact with naïve T and B lymphocytes in the lymph nodes.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following is the receptor that differentiates a cytotoxic T lymphocyte from a helper T lymphocyte?

Accepted Answer

A)  CD8 receptor
B)  CD4 receptor
C)  MHC class I
D)  T cell receptor
E)  B cell receptorF) A) and B)
G) None of the above

Question 4

Which of the following is NOT a peripheral or secondary lymphoid organ?

Accepted Answer

A)  Tonsils
B)  Thymus
C)  Lymph node
D)  Spleen
E)  Peyer's patchesF) A) and D)
G) C) and D)

Question 5

The constant region of an antibody molecule is only located on the light chain.

Accepted Answer

A) True 
 B)False

Question 6

Myxoma virus,a rabbit poxvirus,produces a viroceptor that is a homologue of the interferon- γ\gammaγ receptor.What purpose does this serve the virus?

Accepted Answer

A)  It sequesters the interferon- γ\gammaγ .
B)  It stimulates the host cells to divide.
C)  It enhances the release of virus particles from the infected cell.
D)  It increases virus replication.
E)  It prevents the MHC-I protein from displaying viral peptides. F) A) and C)
G) B) and D)

Question 7

Which of the following types of immunoglobulin molecules is the first to be made during an immune response to a virus infection?

Accepted Answer

A)  IgA
B)  IgD
C)  IgE
D)  IgG
E)  IgMF) A) and D)
G) A) and B)

Question 8

Antibodies are produced by CD4 positive T lymphocytes.

Accepted Answer

A) True 
 B)False

Question 9

Which of the following is a situation where an NK cell can recognize a virally infected cell and kill it?

Accepted Answer

A)  The plasma membrane contains viral glycoproteins.
B)  The NK cell recognizes the MHC-I complex on the surface.
C)  The infected cell displays peptides on MHC-I complexes on its surface
D)  The infected cell has a reduced amount of MHC proteins on its surface.
E)  The NK cell recognizes the virus host cell receptor on the surface of the cell.F) C) and E)
G) B) and E)

Question 10

Which of the following is NOT a component of the adaptive immune response system?

Accepted Answer

A)  B lymphocytes
B)  Helper T lymphocytes
C)  Cytotoxic T lymphocytes
D)  Complement system
E)  AntibodiesF) B) and E)
G) A) and E)

Question 11

The IgG molecule is the most abundant immunoglobulin produced during an immune response.

Accepted Answer

A) True 
 B)False

Question 12

Which of the following statements about MHC class I molecules is FALSE?

Accepted Answer

A)  They are located on the surface of all cells in the body.
B)  They are used to identify the cells as belonging to the host (self-identification) .
C)  They are recognized by natural killer cells.
D)  They present cytoplasmic peptides to cytotoxic T lymphocytes.
E)  They are recognized by B lymphocytes.F) All of the above
G) A) and D)

Question 13

Which of the following describes the primary role of Th1 cells in modulating the immune response?

Accepted Answer

A)  They present foreign antigens to B and T cells.
B)  They engulf virus particles and present peptides on MHC-II.
C)  They release cytokines that stimulate differentiation of cytotoxic T cells.
D)  They release cytokines that stimulate a B cell to differentiate into a plasma cell.
E)  They recognize and kill virus infected cells.F) A) and E)
G) B) and E)

Question 14

What happens when the T cell receptor on a CD8 positive T cell recognizes the peptide displayed in the MHC-I complex on an infected cell?

Accepted Answer

A)  It attracts natural killer cells,which kill the infected cell.
B)  It releases interferon  γ\gammaγ  which stimulates macrophages to engulf the cell.
C)  It releases IL-4 to stimulate the B cells to release antibodies.
D)  It releases proteins that kill the infected cell.
E)  It releases IL-12 which stimulates the production of Th1 cells. F) C) and D)
G) B) and E) D

Question 15

A single plasma cell can secrete two different antibodies that recognize different epitopes.

Accepted Answer

A) True 
 B)False

Question 16

Many viruses reduce the amount of MHC-I complex on the surface of the infected cell.How does the immune system recognize cells that lack MHC-I?

Accepted Answer

A)  Cytotoxic T lymphocytes will recognize the lack of MHC-I on the surface and kill the cell
B)  Macrophages will recognize an antibody bound to MHC-I and engulf the cell.
C)  Natural killer cells will kill cells that lack MHC-I on their surface.
D)  Cells that don't have enough MHC-I on their surface will enter apoptosis and die.
E)  Cytotoxic T lymphocytes will recognized the altered MHC-I on the cell surface.F) A) and E)
G) A) and D)

Question 17

Antigenic drift allows viruses to evade both humoral and cellular immune defenses.

Accepted Answer

A) True 
 B)False

Question 18

The binding of an antibody to a virus particle allows it to be phagocytosed by a macrophage.Which of the following describes the mechanism by which this occurs?

Accepted Answer

A)  The antibody makes the virus particle large enough to be detected by the macrophage.
B)  The macrophage has a receptor that binds to the constant region of the antibody.
C)  The antibody activates the complement system.
D)  The antibody causes the virus particle to be lysed in the endosome.
E)  The antibody causes the virus particle to bind to MHC-IF) A) and C)
G) A) and D)

Question 19

Which of the following describes the structure of the B-cell receptor?

Accepted Answer

A)  It is a type I trans-membrane protein.
B)  It is a type II trans-membrane protein.
C)  It is a membrane bound form of an antibody molecule.
D)  It is composed of two polypeptides,one of which has a trans-membrane domain.
E)  It is composed of two polypeptides,both of which contain trans-membrane domains.F) B) and E)
G) None of the above C

Question 20

Explain why it is more difficult for the immune system to detect and destroy viruses than bacteria.Describe the primary mechanism used by the adaptive immune response to overcome this obstacle.

Accepted Answer

Most bacterial pathogens do not enter ce...

Exam 34: Innate and Adaptive Immune Responses to Virus Infection

Which of the following is NOT an antigen presenting cell?

Correct AnswerverifiedA

Antigen presenting cells,like dendritic cells,interact with naïve T and B lymphocytes in the lymph nodes.

Correct AnswerverifiedShow Answer

Which of the following is the receptor that differentiates a cytotoxic T lymphocyte from a helper T lymphocyte?

Correct AnswerverifiedShow Answer

Which of the following is NOT a peripheral or secondary lymphoid organ?

Correct AnswerverifiedShow Answer

The constant region of an antibody molecule is only located on the light chain.

Correct AnswerverifiedShow Answer

Myxoma virus,a rabbit poxvirus,produces a viroceptor that is a homologue of the interferon- γ\gammaγ receptor.What purpose does this serve the virus?

Correct AnswerverifiedShow Answer

Which of the following types of immunoglobulin molecules is the first to be made during an immune response to a virus infection?

Correct AnswerverifiedShow Answer

Antibodies are produced by CD4 positive T lymphocytes.

Correct AnswerverifiedShow Answer

Which of the following is a situation where an NK cell can recognize a virally infected cell and kill it?

Correct AnswerverifiedShow Answer

Which of the following is NOT a component of the adaptive immune response system?

Correct AnswerverifiedShow Answer

The IgG molecule is the most abundant immunoglobulin produced during an immune response.

Correct AnswerverifiedShow Answer

Which of the following statements about MHC class I molecules is FALSE?

Correct AnswerverifiedShow Answer

Which of the following describes the primary role of Th1 cells in modulating the immune response?

Correct AnswerverifiedShow Answer

What happens when the T cell receptor on a CD8 positive T cell recognizes the peptide displayed in the MHC-I complex on an infected cell?

Correct AnswerverifiedD

A single plasma cell can secrete two different antibodies that recognize different epitopes.

Correct AnswerverifiedShow Answer

Many viruses reduce the amount of MHC-I complex on the surface of the infected cell.How does the immune system recognize cells that lack MHC-I?

Correct AnswerverifiedShow Answer

Antigenic drift allows viruses to evade both humoral and cellular immune defenses.

Correct AnswerverifiedShow Answer

The binding of an antibody to a virus particle allows it to be phagocytosed by a macrophage.Which of the following describes the mechanism by which this occurs?

Correct AnswerverifiedShow Answer

Which of the following describes the structure of the B-cell receptor?

Correct AnswerverifiedC

Explain why it is more difficult for the immune system to detect and destroy viruses than bacteria.Describe the primary mechanism used by the adaptive immune response to overcome this obstacle.

Correct AnswerverifiedMost bacterial pathogens do not enter ce...View AnswerShow Answer

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A

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Myxoma virus,a rabbit poxvirus,produces a viroceptor that is a homologue of the interferon- $\gamma$ receptor.What purpose does this serve the virus?

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Most bacterial pathogens do not enter ce...
View Answer