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Which of the following would cause a decrease in cardiac output?


A) An increase in venous return
B) An increase in afterload
C) Addition of positive inotropic agents
D) An increase in heart rate

E) A) and D)
F) A) and B)

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Large doses of certain stimulants can lead to dangerous increases in heart rates. Such a stimulant is a


A) positive chronotropic agent.
B) negative chronotropic agent.
C) positive inotropic agent.
D) negative inotropic agent.

E) A) and B)
F) A) and C)

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The main functions of the cardiovascular system include the transport and exchange of respiratory gases, nutrients, and wastes throughout the body.

A) True
B) False

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Which circuit of the cardiovascular system is responsible for sending blood to the kidneys, stomach, and pelvic regions?


A) Pulmonary circuit
B) Visceral circuit
C) Coronary circuit
D) Systemic circuit

E) B) and C)
F) None of the above

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Cardiac muscle is able to use a variety of fuel types for cellular respiration.

A) True
B) False

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The hearts nodal cells have a more negative resting potential than neurons do, because nodal cells lack leak channels for sodium and potassium ions.

A) True
B) False

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The internal wall surface of each ventricle displays large, smooth, irregular muscular ridges called


A) conus arteriosus.
B) atrioventricular opening.
C) trabeculae carneae.
D) tendinous cords.
E) pectinate muscles.

F) B) and E)
G) B) and C)

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Which describes the endocardium? A: Has single layer of epithelium B: Has layer of areolar connective tissue C: Epithelial cells are squamous D: Epithelial cells are cuboidal E: Has layer of adipose connective tissue F: Has patches of myocardium


A) a, b, c
B) a, b, d
C) a, d, e
D) a, b, c, e
E) a, e, f

F) B) and E)
G) C) and D)

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The receiving chambers of the heart are the atria, and the forcefully pumping chambers of the heart are the ventricles.

A) True
B) False

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Which valve prevents the backflow of blood into the left ventricle when the ventricles relax?


A) Left atrioventricular valve
B) Aortic semilunar valve
C) Right atrioventricular valve
D) Pulmonary semilunar valve
E) None of the choices is correct.

F) B) and C)
G) A) and D)

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Which pair is located more anteriorly in a heart in normal position?


A) Left atrium and left ventricle
B) Left atrium and right ventricle
C) Right atrium and left atrium
D) Right atrium and right ventricle
E) Right atrium and left ventricle

F) A) and B)
G) None of the above

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The units for perfusion of blood are typically


A) grams per minute.
B) milliliters per minute per gram.
C) milliliters per hour per kilogram.
D) liters per gram.
E) beats per minute per gram.

F) A) and D)
G) A) and C)

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Explain the factors that affect cardiac output. In your answer provide one example of a positive inotropic agent and one example of a positive chronotropic agent. For each of those examples, explain what specifically happens to the cells of the heart when they have their effect.

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CO = SV × HR, so a positive in...

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Parasympathetic innervation influences the heart rate, but generally tends to have no direct effect on the force of contractions.

A) True
B) False

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Which prenatal structure forms the ascending aorta and pulmonary trunk?


A) Truncus arteriosus
B) Sinus venosus
C) Primitive atrium
D) Primitive ventricle
E) Conus cordis

F) C) and E)
G) All of the above

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Nodal cells contain fast voltage-gated calcium channels.

A) True
B) False

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Metabolically, cardiac muscle relies on


A) aerobic metabolism using glycolysis of glycogen to meet most ATP demands.
B) aerobic metabolism using many mitochondria and a rich supply of myoglobin.
C) anaerobic metabolism using glycolytic enzymes to quickly generate ATP.
D) anaerobic metabolism using myoglobin, creatin kinase, and ketone bodies.

E) None of the above
F) B) and C)

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________ innervation increases the rate and the force of heart contraction.

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The serous fluid within the pericardial cavity works to


A) lubricate membranes of the pericardium.
B) slow the heart rate.
C) equalize the pressure in the great vessels.
D) eliminate blood pressure spikes.
E) All of the choices are correct.

F) None of the above
G) A) and C)

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The pericardial cavity is between the


A) heart muscle and serous pericardium.
B) fibrous and serous layers of the pericardium.
C) visceral and parietal layers of the serous pericardium.
D) parietal and myocardial layers of the fibrous pericardium.

E) All of the above
F) B) and D)

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