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A hematologist diagnoses a 34-year-old woman with idiopathic thrombocytic purpura (ITP) . Which of the following symptoms/ characteristics would one expect in this patient?


A) Normal blood count
B) Hypercoagulation
C) Decreased clotting time
D) Abnormal bruising
E) Light menstrual periods

F) A) and E)
G) D) and E)

Correct Answer

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Examination of a normal peripheral blood smear reveals a cell more than twice the diameter of an erythrocyte with a kidneyshaped nucleus. There cells are less than 10%10 \% of the total leukocytes. Which of the following cell types is being described?


A) Monocyte
B) Basophil
C) Eosinophil
D) Neutrophil
E) Lymphocyte

F) C) and D)
G) A) and E)

Correct Answer

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Which cell type has cytoplasmic granules that contain heparin and histamine?


A) Eosinophils
B) Basophils
C) Lymphocytes
D) Monocytes
E) Neutrophils

F) A) and B)
G) A) and C)

Correct Answer

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B

What cell in circulating blood is the precursor to microglia and most antigen-presenting cells?


A) Eosinophil
B) Basophil
C) Lymphocyte
D) Monocyte
E) Mast cell

F) A) and E)
G) D) and E)

Correct Answer

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Which biochemical component of the erythrocyte cell surface is primarily responsible for determining blood type (eg, the A-B-O system) .


A) Fatty acid
B) Carbohydrate
C) Nucleic acid
D) Protein
E) Cholesterol

F) D) and E)
G) C) and E)

Correct Answer

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A 43-year-old anatomy professor is working in her garden, pruning rose bushes without gloves, when a thorn deeply penetrates her forefinger. The next day the area has become infected. She removes the tip of the thorn, but there is still pus remaining at the wound site. Which of the following cells function in the formation of pus?


A) Cells with spherical nuclei and scant cytoplasm
B) Biconcave cells with no nuclei
C) Cells with bilobed nuclei and many acidophilic cytoplasmic granules
D) Very small, cell-like elements with no nuclei but many granules
E) Cells with polymorphic, multiply lobed nuclei

F) A) and D)
G) B) and E)

Correct Answer

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E

What is the approximate life span of a circulating erythrocyte?


A) 8 days
B) 20 days
C) 5 weeks
D) 4 months
E) 1 year

F) A) and B)
G) A) and C)

Correct Answer

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A differential cell count of a blood smear from a patient with a parasitic infection is likely to reveal an increase in the circulating numbers of which cell type?


A) Neutrophils
B) Lymphocytes
C) Monocytes
D) Basophils
E) Eosinophils

F) A) and E)
G) A) and C)

Correct Answer

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E

A 35-year-old woman's physician orders laboratory blood tests. Her fresh blood is drawn and centrifuged in the presence of heparin as an anticoagulant to obtain a hematocrit. From top to bottom, the fractions resulting from centrifugation are which of the following?


A) Serum, packed erythrocytes, and leukocytes
B) Leukocytes, erythrocytes, and serum proteins
C) Plasma, buffy coat, and packed erythrocytes
D) Fibrinogen, platelets, buffy coat, and erythrocytes
E) Albumin, plasma lipoproteins, and erythrocytes

F) B) and E)
G) A) and E)

Correct Answer

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Which of the following blood cells differentiate outside of the bone marrow?


A) Neutrophils
B) Basophils
C) Eosinophils
D) T lymphocytes
E) Megakaryocytes

F) None of the above
G) A) and C)

Correct Answer

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