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Compare the leakage rates of sodium and potassium into and out of a neuron at rest.How is the relationship between these rates best described?


A) Leakage of sodium ions out of the neuron is greater than leakage of potassium ions into the neuron.
B) Leakage of sodium ions into the neuron is greater than leakage of potassium ions out of the neuron.
C) Leakage of potassium ions out of the neuron is greater than leakage of sodium ions into the neuron.
D) Leakage of potassium ions into the neuron is greater than leakage of sodium ions out of the neuron.
E) Leakage of potassium ions out of the neuron is equivalent to leakage of sodium ions into the neuron.

F) A) and E)
G) B) and E)

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The level of the vertebrate nervous system responsible for the skeletal muscle responses to stimuli is the ___________________ system.


A) sensory
B) somatic
C) sympathetic
D) All of these answers are correct.

E) B) and D)
F) A) and D)

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Identify the key feature of the action potential that ensures it will travel only one direction.


A) the activation state of the voltage-gated Na+ channel
B) the inactivation state of the voltage-gated Na+ channel
C) the activation state of the voltage-gated K+ channel
D) the inactivation state of the voltage-gated K+ channel
E) the temporary cessation in activity of the Na+/K+ pump

F) A) and B)
G) A) and C)

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The Nernst Equation is: E = 60 mV log10 ([Xextracellular/Xintracellular]).Given this,the equilibrium potential for a given ion would be increased with an increase in its intracellular concentration.

A) True
B) False

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A neurologist diagnoses a patient with damage to the hippocampus.This observation is consistent with the difficulties the patient reports with


A) forming memories of recent events.
B) effectively coordinating movements once initiated.
C) planning movements.
D) maintaining a steady and regular heartbeat.
E) perceiving tactile stimulation from different regions of their body.

F) All of the above
G) None of the above

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Activities like playing a musical instrument regularly can affect the size of brain regions involved in performing these activities.

A) True
B) False

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The critical function of the sodium-potassium pump of neurons is to move


A) Na+ and K+ into the cell.
B) Na+ and K+ out of the cell.
C) Na+ into the cell and K+ out of the cell.
D) Na+ out of the cell and K+ into the cell.
E) Na+ and K+ into the cell and H+ out of the cell through an antiport mechanism.

F) B) and E)
G) A) and E)

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Synaptic vesicles discharge their contents at the axon hillock region.

A) True
B) False

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Indicate the mechanism responsible for the rapid depolarization that occurs as the "upsweep" of membrane potential peaks during the action potential.


A) closing of the voltage-gated Na+ channel activation gates
B) closing of the voltage-gated Na+ channel inactivation gates
C) opening of the voltage-gated K+ channel gates
D) both opening of the K+ channel gates and closing of the Na+ channel inactivation gates
E) both opening of the K+ channel gates and closing of the Na+ channel activation gates

F) All of the above
G) B) and E)

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Cranial nerves are connected directly to the brain.

A) True
B) False

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Metabotropic receptors act by initiating changes in second messenger systems in target cells.

A) True
B) False

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When a neuron undergoes a change in membrane potential that is proportional to (i.e. ,varies depending on) the strength of the stimulus given to that neuron,this is referred to as a/an


A) equilibrium potential.
B) action potential.
C) resting potential.
D) reversal potential.
E) graded potential.

F) B) and D)
G) D) and E)

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Synaptic vesicles discharge their contents by exocytosis at the


A) dendrite.
B) axon hillock.
C) nodes of Ranvier.
D) postsynaptic membrane.
E) presynaptic membranE.

F) B) and E)
G) All of the above

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The brain region responsible for producing hormones that are secreted by the pituitary gland is the


A) cerebrum.
B) cerebellum.
C) thalamus.
D) hypothalamus.
E) medulla oblongata.

F) A) and B)
G) B) and C)

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(Check all that apply) Depression is usually


A) counteracted with selective serotonin reuptake inhibitors.
B) the result of a neurotransmission disorder
C) counteracted with neurotransmitters that inhibit the secretion of serotonin.
D) found more often in men than in women.

E) None of the above
F) All of the above

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The two broad classes of cells in the nervous system include 1) ) those responsible for information processing,and 2) ) those providing mechanical and metabolic support. These two categories of specialized cells are called


A) microglia and Schwann cells.
B) neurons and glial cells.
C) Schwann cells and glial cells.
D) neurons and fibrocytes.
E) astrocytes and Schwann cells.

F) D) and E)
G) B) and E)

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In a neuron at rest,the membrane is most permeable to


A) potassium.
B) sodium.
C) chloride.
D) calcium.
E) magnesium.

F) B) and E)
G) B) and C)

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The mammalian circadian pacemaker is located in the


A) hypothalamus.
B) brainstem.
C) somatosensory cortex.
D) adrenal glanD.
E) hippocampus.

F) A) and B)
G) A) and D)

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Damage to the cerebellum could result in


A) decreased ability to balance.
B) loss of hearing.
C) loss of vision.
D) loss of taste sensation.
E) diminished thermoreceptive sensation.

F) C) and E)
G) A) and B)

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Propose a valid reason to explain why is it critical that the K+ channel activation gate responds slightly slower to depolarization than the Na+ channel activation gate.


A) If both gates showed identical response times,movements of Na+ and K+ ions would cancel out each other's effects on membrane potential changes.
B) If both gates showed identical response times,movements of Na+ and K+ ions would magnify each other's effects on membrane potential changes,creating dangerously large action potentials.
C) It is not critical and there would be no change in action potential characteristics if this difference in response time did not exist.
D) The conformational change in one gate is necessary to trigger the activation of the other.

E) C) and D)
F) A) and D)

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